Join the Biomaker Challenge 2020 for innovation and discovery!

Table of Contents:

1. Introduction
2. The Biomaker Challenge
3. What is Biomaker?
4. Previous Biomaker Projects 4.1 Instrumentation and Microscopy 4.2 Software Projects 4.3 Microfluidics and 3D Printing 4.4 Cell-Free Biology and Synthetic Biology 4.5 Biomedical and Plant Sciences 4.6 Education and Outreach
5. Francesco's Biomaker Project
6. How Does Biomaker Work?
7. Timeline and Deadlines
8. What Participants Can Expect
9. Eligibility Criteria
10. How to Apply
11. Conclusion

The Biomaker Challenge: Promoting Interdisciplinary Innovation in Synthetic Biology

Synthetic biology is an emerging field that combines biology, engineering, and computer science to design and construct new biological functions and systems. The Biomaker Challenge, an annual event organized by the University of Cambridge Synthetic Biology Network and Open Plant, aims to foster innovation in synthetic biology by funding interdisciplinary projects that bring together biologists, engineers, and computer scientists.

Introduction

Welcome to the 2020 Biomaker Challenge briefing! My name is Stephanie Nord, the events coordinator for the University of Cambridge Synthetic Biology Network and Open Plant. In this briefing, I will provide an overview of the Biomaker Challenge, including its objectives, application process, and the various benefits it offers to participants. Joining me is Professor Jim Hasselov, who will share more insights into the history and significance of the Biomaker Challenge.

The Biomaker Challenge

The Biomaker Challenge is an annual event that has been running for several years, evolving from project-Based learning exercises in the iGEM competition to a broader, interdisciplinary activity centered around biomaker projects. Funded by Open Plant and several UK research councils, the challenge aims to bring together individuals from diverse backgrounds to explore the integration of electronics, sensors, and biology in innovative ways.

What is Biomaker?

Biomaker is a project funding initiative that supports interdisciplinary teams consisting of biologists, engineers, computer scientists, and other experts. The initiative provides funding and support to these teams, allowing them to work on ambitious projects that Blend different disciplines and address real-world applications. Biomaker projects cover a wide range of areas, including instrumentation, microscopy, software development, microfluidics, 3D printing, cell-free biology, synthetic biology, biomedical sciences, plant sciences, and education/outreach.

Previous Biomaker Projects

Over the years, Biomaker has funded over 80 projects, each unique in its concept and scope. These projects have spanned a diverse range of topics, showcasing the creative and innovative nature of interdisciplinary collaboration. Some notable areas that Biomaker projects have explored include:

4.1 Instrumentation and Microscopy

Projects focused on developing Novel instruments and microscopy techniques for biological research. These projects involved the integration of advanced hardware, software, and imaging technologies to enable precise and high-resolution imaging.

4.2 Software Projects

Several Biomaker projects have concentrated on developing software solutions for analyzing and modeling biological data. These projects leveraged the power of computer science and machine learning algorithms to enhance data processing and interpretation.

4.3 Microfluidics and 3D Printing

The combination of microfluidics and 3D printing has unlocked new possibilities in the creation of functional biological devices. Biomaker projects in this area explored the fabrication of custom microfluidic systems and the integration of 3D-printed components into biological experiments.

4.4 Cell-Free Biology and Synthetic Biology

Cell-free biology and synthetic biology projects aimed to engineer synthetic biological systems outside the confines of living cells. These projects focused on designing novel genetic circuits, developing cell-free expression systems, and harnessing the power of synthetic biology tools.

4.5 Biomedical and Plant Sciences

Biomaker's interdisciplinary approach also extended to the medical and agricultural fields. Projects in biomedical sciences explored the development of innovative diagnostic tools and therapies, while plant science projects focused on enhancing crop productivity and resilience through genetic engineering.

4.6 Education and Outreach

Biomaker recognizes the importance of scientific education and public engagement. Several projects have been dedicated to developing educational resources, hands-on workshops, and outreach activities to inspire the next generation of synthetic biologists.

To gain more inspiration and see the variety of compelling Biomaker projects, visit our Website or explore the Hackster page dedicated to documenting these projects.

Francesco's Biomaker Project

Francesco Ciriello, a participant in a previous Biomaker challenge, shared his experience and insights into the project he led. As a postdoctoral researcher in the engineering department at the University of Cambridge, Francesco specialized in fluid mechanics. His project, called Lunaflow, focused on studying the behavior of planktonic microorganisms called dinoflagellates. The team sought to grow these microorganisms and utilize their ability to emit Blue light for microscopic fluid flow measurement. They developed an innovative incubator and a multi-camera system to study and Record the flow Patterns created by the dinoflagellates.

Francesco's project exemplifies the interdisciplinary nature of Biomaker projects and highlights their potential impact in various fields.

How Does Biomaker Work?

Biomaker follows a well-defined timeline and series of activities to support successful project development. Here is a brief overview of the Biomaker process:

1. Team Formation: Participants Gather a team of individuals with diverse expertise, including biologists, engineers, and computer scientists. Teams should aim for interdisciplinary collaboration.

2. Proposal Submission: Each team is required to submit a short proposal detailing their project's objectives, methodology, budget, and feasibility. The proposal should include a clear biological application and demonstrate how different disciplines will be integrated.

3. Funding and Support: Successful teams will be awarded a Biomaker expansion kit and additional hardware, along with funding totaling £1,000. Teams will also receive training materials, workshops, and support in using software platforms like SoC.

4. Initial Project Development: Teams will have a month and a half to start working on their projects, documenting their progress, and preparing for the interim report submission. This period allows teams to refine their ideas, procure necessary materials, and commence project development.

5. Interim Report and Additional Funding: In January, teams will present an interim report, showcasing their project's progress. They will also have the opportunity to pitch for additional funding, with up to £2,000 available for further project development.

6. Final Exhibition and Report: In April 2021, all teams will gather at the Open Plant Forum for a final exhibition. Teams will share their project outcomes, present a final report, and have the chance to network with other participants and experts in the field.

Through this well-structured process, Biomaker aims to nurture innovation and collaboration while providing teams with essential resources, guidance, and opportunities for further funding.

Timeline and Deadlines

To ensure a smooth execution of the Biomaker Challenge, teams must adhere to the following timeline:

• Today: Attend the briefing and mixer event to meet potential team members and discuss project ideas.
• Within Three Weeks: Form your team and initiate discussions on project ideas. Consider the interdisciplinary nature of the project and identify team members with complementary skill sets.
• By December 6th: Submit your short proposal, highlighting the project's objectives, methodology, budget, and feasibility.
• By December 11th: Successful teams will be notified, and arrangements will be made to provide the Biomaker expansion kit, additional hardware, and funding.
• Mid-December to End of January: Begin project development, document progress, and prepare for the interim report.
• By the end of January: Submit the interim report, showcasing your project's progress and providing an opportunity to pitch for additional funding.
• January to April: If successful in pitching for further funding, teams will have three months to Continue project development and refine their ideas.
• April 2021: Attend the Open Plant Forum for a final exhibition, present project outcomes, and network with other participants and experts.

By adhering to these deadlines, teams can stay on track and maximize their chances of success in the Biomaker Challenge.

What Participants Can Expect

By participating in the Biomaker Challenge, individuals and teams can expect numerous benefits and opportunities. These include:

1. Learning Opportunities: The Biomaker Challenge offers a chance to acquire new skills and gain hands-on experience with cutting-edge technologies. Participants will have access to training materials, workshops, and support in using software platforms like SoC.

2. Funding and Resources: Each participant will receive a Biomaker expansion kit, comprising an extended Arduino board and a goody bag of useful sensors and devices. Teams will also be allocated a budget of £800 to purchase additional equipment, consumables, and materials.

3. Interdisciplinary Collaboration: Biomaker encourages individuals from diverse backgrounds to collaborate and work as interdisciplinary teams. This environment fosters creative thinking, innovative problem-solving, and the development of groundbreaking projects.

4. Networking and Exposure: Throughout the Biomaker Challenge, participants will have the opportunity to network with fellow researchers, industry experts, and potential collaborators. The final exhibition at the Open Plant Forum provides a platform to showcase their projects to a wider audience.

5. Project Documentation and Open Access: Biomaker emphasizes the importance of open access and documentation. Participants are expected to document their projects on the Hackster platform, making their work accessible and reusable by others.

By actively participating in the Biomaker Challenge, individuals can broaden their skillset, accelerate their learning, collaborate with experts in different fields, and gain exposure in the scientific community.

Eligibility Criteria

To be eligible to participate in the Biomaker Challenge, teams must meet the following criteria:

1. Membership: Each team must have at least one member who is either a student or staff at the University of Cambridge, John Innes Centre, or the Earlham Institute in Norwich.

2. Interdisciplinary Teams: Biomaker encourages the formation of interdisciplinary teams consisting of individuals from various disciplines, enabling an exchange of expertise and perspectives.

3. Bridging Institutes: To foster collaboration and innovation, Biomaker encourages teams to bridge the gap between Cambridge and Norwich institutes.

4. Open Access: All projects funded by Biomaker must be open access and easily accessible to others, allowing for replication and innovation.

By meeting these criteria, teams can ensure their eligibility and maximize their chances of receiving funding and support from Biomaker.

How to Apply

Applying for the Biomaker Challenge involves the following steps:

1. Team Formation: Gather a team of individuals with diverse expertise, including biologists, engineers, and computer scientists. Consider reaching out to potential team members during the briefing and mixer event.

2. Proposal Submission: Create a short proposal using the provided template. The proposal should clearly Outline the project's objectives, methodology, budget, and feasibility. Address the interdisciplinary nature of the project and its potential impact.

3. Submitting the Proposal: Submit the proposal by the specified deadline (December 6th). Templates and submission details can be found on the Biomaker website.

4. Evaluation and Notification: A panel of judges will evaluate the proposals based on interdisciplinarity, biological application, feasibility, and innovation. Successful teams will be notified by December 11th.

By following these steps and presenting a well-defined and innovative proposal, teams can increase their chances of being selected for the Biomaker Challenge.

Conclusion

The Biomaker Challenge offers a unique opportunity for individuals from diverse backgrounds, including biologists, engineers, and computer scientists, to collaborate on interdisciplinary projects in the field of synthetic biology. By providing funding, resources, and support, Biomaker empowers teams to explore innovative applications and develop groundbreaking projects. Through open access and documentation, Biomaker encourages the wider scientific community to replicate and build upon the outcomes of its projects. Take the first step in this exciting Journey, form your team, and submit a proposal that showcases your passion and expertise in pushing the boundaries of synthetic biology.

Allow Biomaker to unlock your potential as an interdisciplinary innovator and make a lasting impact in the field of synthetic biology.

Highlights:

• The Biomaker Challenge promotes interdisciplinary collaboration in synthetic biology.
• Biomaker funds projects that integrate electronics, sensors, and biology.
• Previous Biomaker projects cover a wide range of areas, including instrumentation, software development, microfluidics, cell-free biology, and plant sciences.
• Francesco's Biomaker project focused on studying dinoflagellates and developing an incubator and multi-camera system.
• Biomaker follows a timeline that includes team formation, proposal submission, project development, and final exhibition.
• Participants can expect learning opportunities, funding, interdisciplinary collaboration, networking, and project documentation.
• Eligibility criteria include membership at partner institutes, interdisciplinary teams, bridging institutes, and open access projects.
• Applying for Biomaker involves team formation, proposal creation, submission, and evaluation.
• Biomaker provides a unique opportunity to push the boundaries of synthetic biology and make a lasting impact.

FAQ:

Q: Can individuals from institutes not affiliated with the Biomaker Challenge participate? A: Yes, individuals from other institutes can participate by forming teams with at least one member from a partner institute.

Q: Is there a specific budget for hardware and consumables? A: Biomaker provides a total funding amount of £1,000, with approximately £200 allocated for the hardware expansion kit and £800 for purchasing additional equipment and consumables.

Q: Can I apply for Biomaker without a fully-formed team? A: Yes, you can form a team after attending the briefing and mixer event. Biomaker can help connect you with potential team members.

Q: Are there particular areas of interest that Biomaker is prioritizing this year? A: Biomaker is particularly interested in projects related to cell-free synthetic biology, plant science, and sensor technologies. However, innovative projects from other areas are also encouraged.

Q: Is there funding available for projects beyond the initial funding phase? A: Yes, teams can pitch for additional funding of up to £2,000 to continue project development and refinement.

Q: How can I access training materials and support for using software platforms? A: Biomaker provides training materials, workshops, and support for software platforms such as SoC. These resources will be available to participants throughout the challenge.

Q: Can I collaborate with individuals from different institutes, even if they are not from Cambridge or Norwich? A: Yes, Biomaker encourages collaboration across different institutes and locations to foster interdisciplinary collaboration.